| Michigan St. Games/Schedule |
| Regular Season |
| Nov. 4, 2025 | Day 2 | Mercyhurst - Michigan St. (15) | 39-125  |
| Nov. 9, 2025 | Day 7 | EMU - Michigan St. (15) | 60-92 |
| Nov. 12, 2025 | Day 10 | YSU - Michigan St. (15) | 52-96 |
| Nov. 16, 2025 | Day 14 | W.Michigan - Michigan St. (15) | 44-98 |
| Nov. 20, 2025 | Day 18 | EIU - Michigan St. (15) | 53-101 |
| Nov. 23, 2025 | Day 21 | Oakland - Michigan St. (15) | 41-102 |
| Nov. 28, 2025 | Day 26 | Temple - Michigan St. (15) | 50-85 |
| Nov. 30, 2025 | Day 28 | Michigan St. (15) - Clemson | 72-64 |
| Dec. 7, 2025 | Day 35 | Michigan St. (15) - Wisconsin | 64-78  |
| Dec. 14, 2025 | Day 42 | Michigan St. (15) - DePaul | 90-46 |
| Dec. 21, 2025 | Day 49 | Indiana St. - Michigan St. (15) | 66-115 |
| Dec. 22, 2025 | Day 50 | Ole Miss (16) - Michigan St. (15) | 49-66 |
| Dec. 28, 2025 | Day 53 | Rutgers - Michigan St. (15) | 64-70 |
| Jan. 1, 2026 | Day 57 | Michigan St. (15) - Indiana | 80-60 |
| Jan. 4, 2026 | Day 60 | Illinois (25) - Michigan St. (15) | 75-81 |
| Jan. 8, 2026 | Day 64 | Michigan St. (15) - Washington | 82-67 |
| Jan. 11, 2026 | Day 67 | Michigan St. (15) - Oregon | 85-81 |
| Jan. 15, 2026 | Day 71 | Nebraska (24) - Michigan St. (15) | 71-73 |
| Jan. 18, 2026 | Day 74 | Michigan St. (15) - Iowa (11) | 68-75 |
| Jan. 22, 2026 | Day 78 | USC - Michigan St. (15) | 68-74 |
| Jan. 29, 2026 | Day 85 | Michigan St. (15) - Purdue | 86-65 |
| Feb. 1, 2026 | Day 88 | Michigan (8) - Michigan St. (15) | 94-91 |
| Feb. 4, 2026 | Day 91 | Maryland (12) - Michigan St. (15) | 86-70 |
| Feb. 7, 2026 | Day 94 | Michigan St. (15) - Penn State | 81-70 |
| Feb. 11, 2026 | Day 98 | UCLA (3) - Michigan St. (15) | 86-63 |
| Feb. 15, 2026 | Day 102 | Michigan St. (15) - Michigan (8) | 65-86 |
| Feb. 18, 2026 | Day 105 | Northwestern - Michigan St. (15) | 68-104 |
| Feb. 22, 2026 | Day 109 | Michigan St. (15) - Minnesota | 75-61 |
| Mar. 1, 2026 | Day 116 | Ohio St. (14) - Michigan St. (15) | 87-68 |
| Mar. 5, 2026 | Day 120 | Illinois (25) - Michigan St. (15) | 71-69 |
| National Tournament Day 1 |
| Mar. 20, 2026 | Day 1 | Colorado St. - Michigan St. (15) | 62-65 |
| National Tournament Day 2 |
| Mar. 22, 2026 | Day 1 | Michigan St. (15) - Oklahoma (13) | 71-77 |
