| Notre Dame Games/Schedule |
| Regular Season |
| Nov. 7, 2022 | Day 7 | NIU - Notre Dame (11) | 48-88  |
| Nov. 12, 2022 | Day 12 | California - Notre Dame (11) | 79-90 |
| Nov. 16, 2022 | Day 16 | Notre Dame (11) - Northwestern | 92-58 |
| Nov. 20, 2022 | Day 20 | Ball St. - Notre Dame (11) | 60-95 |
| Nov. 24, 2022 | Day 24 | Notre Dame (11) - American | 90-65 |
| Nov. 26, 2022 | Day 26 | Notre Dame (11) - Arizona St. | 85-65 |
| Dec. 1, 2022 | Day 31 | Maryland (5) - Notre Dame (11) | 74-72  |
| Dec. 4, 2022 | Day 34 | UConn (9) - Notre Dame (11) | 60-74 |
| Dec. 10, 2022 | Day 40 | Merrimack - Notre Dame (11) | 44-108 |
| Dec. 18, 2022 | Day 48 | Notre Dame (11) - Virginia Tech (4) | 63-52 |
| Dec. 21, 2022 | Day 51 | W.Michigan - Notre Dame (11) | 57-85 |
| Dec. 29, 2022 | Day 56 | Notre Dame (11) - Miami, FL (18) | 66-63 |
| Jan. 1, 2023 | Day 59 | Boston Coll. - Notre Dame (11) | 48-85 |
| Jan. 8, 2023 | Day 66 | Notre Dame (11) - UNC (21) | 50-60 |
| Jan. 12, 2023 | Day 70 | Wake Forest - Notre Dame (11) | 47-86 |
| Jan. 15, 2023 | Day 73 | Notre Dame (11) - Syracuse | 72-56 |
| Jan. 19, 2023 | Day 77 | Notre Dame (11) - Clemson | 57-54 |
| Jan. 22, 2023 | Day 80 | Virginia - Notre Dame (11) | 54-76 |
| Jan. 26, 2023 | Day 84 | FSU - Notre Dame (11) | 47-70 |
| Jan. 29, 2023 | Day 87 | Notre Dame (11) - NC State | 65-69 |
| Feb. 2, 2023 | Day 91 | Notre Dame (11) - Boston Coll. | 72-59 |
| Feb. 5, 2023 | Day 94 | Duke (16) - Notre Dame (11) | 57-52 |
| Feb. 9, 2023 | Day 98 | Pittsburgh - Notre Dame (11) | 63-69 |
| Feb. 12, 2023 | Day 101 | Syracuse - Notre Dame (11) | 64-73 |
| Feb. 16, 2023 | Day 104 | Louisville - Notre Dame (11) | 76-78 |
| Feb. 19, 2023 | Day 107 | Notre Dame (11) - Pittsburgh | 83-43 |
| Feb. 23, 2023 | Day 111 | Georgia Tech - Notre Dame (11) | 53-76 |
| Feb. 26, 2023 | Day 114 | Notre Dame (11) - Louisville | 68-65 |
| Conference Quarter-Finals |
| Mar. 3, 2023 | Day 1 | NC State - Notre Dame (11) | 60-66 |
| Conference Semi-Finals |
| Mar. 4, 2023 | Day 1 | Louisville - Notre Dame (11) | 64-38 |
| National Tournament Day 1 |
| Mar. 17, 2023 | Day 1 | SUU - Notre Dame (11) | 56-82 |
| National Tournament Day 2 |
| Mar. 19, 2023 | Day 2 | MSU - Notre Dame (11) | 48-53 |
| National Tournament Day 3 |
| Mar. 25, 2023 | Day 3 | Notre Dame (11) - Maryland (5) | 59-76 |
