| Louisville Games/Schedule |
| Regular Season |
| Nov. 15, 2015 | Day 3 | Louisville (8) - California | 71-75  |
| Nov. 21, 2015 | Day 9 | W.Kentucky - Louisville (8) | 71-69 |
| Nov. 27, 2015 | Day 15 | Louisville (8) - Marist | 65-53  |
| Nov. 28, 2015 | Day 16 | Louisville (8) - Purdue | 60-62 |
| Nov. 29, 2015 | Day 17 | Dayton - Louisville (8) | 79-66 |
| Dec. 3, 2015 | Day 21 | Michigan St. (16) - Louisville (8) | 78-85 |
| Dec. 5, 2015 | Day 23 | Louisville (8) - Valparaiso | 75-42 |
| Dec. 10, 2015 | Day 28 | Kentucky (12) - Louisville (8) | 72-54 |
| Dec. 13, 2015 | Day 31 | Louisville (8) - IUPUI | 70-61 |
| Dec. 15, 2015 | Day 33 | Louisville (8) - Dartmouth | 94-52 |
| Dec. 18, 2015 | Day 36 | Tenn Tech - Louisville (8) | 54-76 |
| Dec. 20, 2015 | Day 38 | Charleston - Louisville (8) | 67-71 |
| Dec. 28, 2015 | Day 43 | Louisville (8) - Tenn-Martin | 88-66 |
| Jan. 1, 2016 | Day 47 | Louisville (8) - Florida St. (17) | 79-69 |
| Jan. 3, 2016 | Day 49 | Georgia Tech - Louisville (8) | 65-78 |
| Jan. 7, 2016 | Day 53 | Louisville (8) - Virginia Tech | 56-45 |
| Jan. 10, 2016 | Day 56 | Louisville (8) - Duke | 65-48 |
| Jan. 14, 2016 | Day 60 | Louisville (8) - Virginia | Last 5 Games |
| Jan. 17, 2016 | Day 63 | N.Carolina St. - Louisville (8) | 90-92 |
| Jan. 25, 2016 | Day 71 | Syracuse (14) - Louisville (8) | 53-71 |
| Jan. 28, 2016 | Day 74 | Louisville (8) - Clemson | 75-33 |
| Jan. 31, 2016 | Day 77 | Louisville (8) - Wake Forest | 78-54 |
| Feb. 4, 2016 | Day 81 | Louisville (8) - N.Carolina | Last 5 Games |
| Feb. 7, 2016 | Day 84 | Louisville (8) - Notre Dame (2) | 61-66 |
| Feb. 11, 2016 | Day 88 | Pittsburgh - Louisville (8) | 61-84 |
| Feb. 15, 2016 | Day 92 | S.Florida (21) - Louisville (8) | 50-67 |
| Feb. 18, 2016 | Day 95 | Virginia - Louisville (8) | 59-74 |
| Feb. 21, 2016 | Day 98 | Louisville (8) - Boston Coll. | 55-45 |
| Feb. 25, 2016 | Day 102 | Louisville (8) - Miami, FL (20) | 79-51 |
| Feb. 28, 2016 | Day 105 | Pittsburgh - Louisville (8) | 36-65 |
| Mar. 4, 2016 | Day 110 | Georgia Tech - Louisville (8) | 50-60 |
| Mar. 5, 2016 | Day 111 | Syracuse (14) - Louisville (8) | 80-75 |
| National Tournament Day 1 |
| Mar. 18, 2016 | Day 122 | Cent.Arkansas - Louisville (8) | 60-87 |
| National Tournament Day 2 |
| Mar. 20, 2016 | Day 124 | De Paul (18) - Louisville (8) | 73-72 |
