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| 2020-2021 |  | Previous season |
Greek League Games/Schedule (2021-2022)
| Melissia Games/Schedule | |||||||
| Regular Season | |||||||
| Oct. 17, 2021 | Round 2 | Doukas - Melissia | 77-80  | ||||
| Oct. 24, 2021 | Round 3 | Melissia - P.Faliro | 61-62  | ||||
| Nov. 3, 2021 | Round 4 | Melissia - AOK Chania | 64-81 | ||||
| Nov. 7, 2021 | Round 5 | Panionios - Melissia | 81-75 | ||||
| Nov. 14, 2021 | Round 6 | Melissia - Ilysiakos | 63-60 | ||||
| Nov. 21, 2021 | Round 7 | Mandraikos - Melissia | 66-55 | ||||
| Nov. 28, 2021 | Round 8 | Melissia - Proteas V. | 53-60 | ||||
| Dec. 5, 2021 | Round 9 | Megaridas - Melissia | 72-59 | ||||
| Dec. 12, 2021 | Round 10 | Melissia - Zografou | 69-75 | ||||
| Dec. 22, 2021 | Round 12 | Melissia - Kronos AD | 74-61 | ||||
| Jan. 23, 2022 | Round 13 | Aris Nikaias - Melissia | 70-63 | ||||
| Jan. 30, 2022 | Round 14 | Melissia - Egaleo | 72-82 | ||||
| Feb. 6, 2022 | Round 15 | Melissia - Doukas | 65-70 | ||||
| Feb. 13, 2022 | Round 16 | P.Faliro - Melissia | 75-48 | ||||
| Feb. 20, 2022 | Round 17 | AOK Chania - Melissia | 97-76 | ||||
| Feb. 27, 2022 | Round 18 | Melissia - Panionios | 62-68 | ||||
| Mar. 6, 2022 | Round 19 | Ilysiakos - Melissia | 56-59 | ||||
| Mar. 20, 2022 | Round 21 | Proteas V. - Melissia | 83-54 | ||||
| Mar. 27, 2022 | Round 22 | Melissia - Megaridas | 61-73 | ||||
| Apr. 3, 2022 | Round 23 | Zografou - Melissia | 86-60 | ||||
| Apr. 10, 2022 | Round 24 | Melissia - OFI | 44-67 | ||||
| Apr. 17, 2022 | Round 25 | Kronos AD - Melissia | 93-75 | ||||
| May. 8, 2022 | Round 27 | Egaleo - Melissia | 98-82 | ||||
