| Indiana Tech Games/Schedule |
| Regular Season |
| Oct. 29, 2021 | Day 16 | IWU (7) - Indiana Tech (25) | 90-82  |
| Oct. 30, 2021 | Day 17 | Spring Arbor - Indiana Tech (25) | 66-72  |
| Nov. 3, 2021 | Day 21 | Indiana Tech (25) - St.Francis, IN (16) | 78-84 |
| Nov. 6, 2021 | Day 24 | IU Northwest - Indiana Tech (25) | 65-100 |
| Nov. 10, 2021 | Day 28 | Indiana Tech (25) - Cornerstone | 76-88 |
| Nov. 13, 2021 | Day 31 | Indiana Tech (25) - Concordia, MI | 78-73 |
| Nov. 17, 2021 | Day 35 | Lourdes - Indiana Tech (25) | 74-65 |
| Nov. 20, 2021 | Day 38 | Indiana Tech (25) - Rochester, MI | 61-57 |
| Nov. 23, 2021 | Day 41 | Indiana Tech (25) - Aquinas Coll. | 60-49 |
| Nov. 27, 2021 | Day 44 | Indiana Tech (25) - Union, KY | 67-50 |
| Nov. 28, 2021 | Day 45 | Warner - Indiana Tech (25) | 54-58 |
| Dec. 1, 2021 | Day 48 | UM-Dearborn - Indiana Tech (25) | 76-111 |
| Dec. 4, 2021 | Day 51 | UNOH - Indiana Tech (25) | 53-78 |
| Dec. 7, 2021 | Day 54 | Indiana Tech (25) - Taylor | 69-45 |
| Dec. 9, 2021 | Day 56 | Huntington - Indiana Tech (25) | 79-76 |
| Dec. 11, 2021 | Day 58 | Lawrence Tech - Indiana Tech (25) | 54-70 |
| Dec. 20, 2021 | Day 67 | Rio Grande - Indiana Tech (25) | 47-64 |
| Dec. 30, 2021 | Day 73 | IWU (7) - Indiana Tech (25) | 91-71 |
| Jan. 8, 2022 | Day 82 | Madonna - Indiana Tech (25) | 76-79 |
| Jan. 12, 2022 | Day 86 | Indiana Tech (25) - SHU | 71-56 |
| Jan. 15, 2022 | Day 89 | Concordia, MI - Indiana Tech (25) | 43-84 |
| Jan. 19, 2022 | Day 93 | Cornerstone - Indiana Tech (25) | 65-71 |
| Jan. 22, 2022 | Day 96 | Indiana Tech (25) - UM-Dearborn | 92-74 |
| Jan. 26, 2022 | Day 100 | Aquinas Coll. - Indiana Tech (25) | 56-66 |
| Jan. 29, 2022 | Day 103 | Rochester, MI - Indiana Tech (25) | 53-69 |
| Feb. 5, 2022 | Day 110 | Indiana Tech (25) - UNOH | 76-62 |
| Feb. 9, 2022 | Day 114 | SHU - Indiana Tech (25) | 54-74 |
| Feb. 12, 2022 | Day 117 | Indiana Tech (25) - Madonna | 80-75 |
| Feb. 14, 2022 | Day 119 | Indiana Tech (25) - Lourdes | 80-69 |
| Feb. 19, 2022 | Day 124 | Indiana Tech (25) - Lawrence Tech | 79-73 |
| Feb. 23, 2022 | Day 128 | UNOH - Indiana Tech (25) | 52-85 |
| Feb. 26, 2022 | Day 131 | Lourdes - Indiana Tech (25) | 89-79 |
| National Tournament Day 1 |
| Mar. 11, 2022 | Day 136 | Southwestern, KS - Indiana Tech (25) | 61-70 |
| National Tournament Day 2 |
| Mar. 12, 2022 | Day 137 | Indiana Tech (25) - IWU (7) | 47-70 |
